CDNF is a member of the ARMET family and acts as a trophic factor for neurons.
CDNF inhibits the (6-OHDA)-induced degeneration of neurons.
When CDNF controlled after 6-OHDA-lesioning, it reestablishes the function and inhibits the degeneration of neurons in substantia nigra.
CDNF is universally expressed in neuronal and non-neuronal tissues.
The highest levels in the brain are found in the optic nerve and corpus callosum.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 20.4 kDa.
The protein migrates as 20-21 kDa and 24-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：500ug
Source：Human CDNF Protein, His Tag, premium grade (CDF-H52H4) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Leu 187 (Accession # Q49AH0).
