Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion.
TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 63.5kDa.
The protein migrates as 85-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Biotinylated Human TPBG protein, Fc,Avitag (TPG-H82F6) is expressed from human 293 cells (HEK293). It contains AA Ser 32 - Ser 355 (Accession # Q13641-1).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc & C-Avi
Exp Region：Ser 32 - Ser 355
Format：Powder
Conjugate：Biotin-labeled
Swiss-Prot：Q13641-1
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
