As one of the five designated immunoglobulin isotypes, immunoglobulin E (IgE) plays a major role in atopic conditions by inducing immediate hypersensitivity reactions.
IgE also contributes significantly to the body’s immune response to parasitic infections.
IgE antibodies are predominantly found in the tissues, firmly attached to effector cells, such as mast cells and basophils, by high-affinity IgE Fc receptor (Fc epsilon RI) and low-affinity IgE receptor (Fc epsilon RII).
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 37.3 kDa.
The protein migrates as 45-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Cynomolgus IgE Fc Protein, His Tag (IGE-C52H3) is expressed from human 293 cells (HEK293). It contains AA Pro 111 - Lys 429 (Accession # G8F4W7).
