Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily.
Cadherins are calcium-dependent cell adhesion proteins.
They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
CDH6 / KCAD contains five cadherin domains.
CDH6 is highly expressed in brain, cerebellum, and kidney.
Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 70.0 kDa.
The protein migrates as 53 kDa, 65 kDa and 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human Cadherin-6 Protein, His,Avitag (CA6-H82E3) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Ala 615 (Accession # P55285-1).
