This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17.
Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes.
The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide.
This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils.
This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 10.1 kDa.
The protein migrates as 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
仕様
容量：100ug
Source：Human CCL11 Protein, His Tag (CC1-H51H3) is expressed from E. coli cells. It contains AA Gly 24 - Pro 97 (Accession # P51671).
