This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins.
Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.
The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer.
This protein plays a role in the development of the nervous and other organ systems, and may regulate aging.
特徴
This protein carries no "tag".
The protein has a calculated MW of 12.6 kDa.
The protein migrates as 11-12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE).
仕様
容量：20ug
Source：Human GDF-11 Protein, premium grade (GD1-H5115) is expressed from E. coli cells. It contains AA Asn 299 - Ser 407 (Accession # O95390).
