The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention.
The Human HLA-A*0201 KRASG12V (KLVVVGAVGV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and KLVVVGAVGV peptide of the KRASG12V.
特徴
Biotinylated Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide.This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).The protein has a calculated MW of 36.3 kDa and 11.7 kDa.
The protein migrates as 40-43 kDa and 10 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Complex Protein (HLV-H82E3) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KLVVVGAVGV peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & KLVVVGAVGV).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His & C-Avi
Exp Region：Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KLVVVGAVGV peptide
