83-3886-35　Human Matriptase / ST14 Catalytic Domain Protein, His Tag （active enzyme） 1mg　MAE-H5143-1mg

特徴

• 背景
• Degrades extracellular matrix.
• Proposed to play a role in breast cancer invasion and metastasis.
• Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
• Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing; Cleaves various synthetic substrates with Arg or Lys at the P1 position and prefers small side-chain amino acids, such as Ala and Gly, at the P2 position.
• 特徴
• This protein carries a polyhistidine tag at the N-terminus.
• The protein has a calculated MW of 30.6 kDa.
• The protein migrates as 27-28 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

仕様

• 容量：1mg
• Source：Human Matriptase / ST14 Catalytic Domain Protein, His Tag (MAE-H5143) is expressed from E. coli cells. It contains AA Gly 596 - Val 855 (Accession # NP_068813).
• Species Reactivity：Human
• Host：E. coli
• Tag：N-10×His
• Exp Region：Gly 596 - Val 855
• Format：Liquid
• Conjugate：Unconjugated
• Swiss-Prot：NP_068813
• Endotoxin：1.0 EU per μg
• Purity：90%
• Buffer：50 mM Tris, 150 mM NaCl, pH 7.5
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