This gene encodes a member of a family of solute transporter proteins.
The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system.
Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors.
Improper regulation of this gene is thought to be associated with several neurological disorders.
Alternatively spliced transcript variants of this gene have been identified.
[provided by RefSeq, Jun 2017]
特徴
This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus.
The protein has a calculated MW of 66.0 kDa.
The protein migrates as 55-116 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human SLC1A2 Protein, Flag,His Tag (SL2-H52D6) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Lys 574 (Accession # P43004).
