The MAGE-A3 antigen is a cancer-testis antigen and is expressed intracellularly in various solid tumor tissues, MAGE-A3 112-120 peptide (KVAELVHFL) is a cytotoxic T lymphocyte (CTL) epitope presented by HLA-A*0201.
The Human HLA-A*0201 MAGE-A3 (KVAELVHFL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and KVAELVHFL peptide of the MAGE-A3.
特徴
Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Complex Protein is produced by co-expression of HLA and B2M loaded with MAGE-A3 peptide.This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).The protein has a calculated MW of 36.3 kDa and 11.7 kDa.
The protein migrates as 38-44 kDa and 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:200ug
Source:Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Complex Protein (HLM-H82E3) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KVAELVHFL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & KVAELVHFL).
Species Reactivity:Human
Host:HEK293
Tag:C-10×His & C-Avi
Exp Region:Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & KVAELVHFL peptide