Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family.
IFNAR1 /IFNAR contains four fibronectin type-III domains.
IFNAR1 associates with IFNAR2 to form the type I interferon receptor.
IFNAR1 is receptor for interferons alpha and beta.
IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 50 kDa.
The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:25ug
Source:Biotinylated Human IFN-alpha / beta R1 Protein, His,Avitag (IF1-H82E3) is expressed from human 293 cells (HEK293). It contains AA Lys 28 - Lys 436 (Accession # P17181-1).