EREG is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4), which stimulates tyrosine phosphorylation of EGFR and ERBB4.
EREG may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation.
Additionally, EREG may promote the progression of cancers of various human tissue.
特徴
This protein carries a human IgG1 Fc tag at the N-terminus.
The protein has a calculated MW of 31.7 kDa.
The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human EREG Protein, Fc Tag (ERG-H5264) is expressed from human 293 cells (HEK293). It contains AA Val 63 - Leu 108 (Accession # O14944-1).
