Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions.
Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5.
As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5.
Furthermore, LTBR may play a role in the development of lymphoid organs.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 24.3 kDa.
The protein migrates as 29 kDa 31-33 kDa and 34-38 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Cynomolgus LTBR / TNFRSF3 Protein, His Tag (LTR-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 28 - Thr 229 (Accession # A0A2K5VGQ6).
