TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha.
It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha.
The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
TNFR2 mediates most of the metabolic effects of TNF-alpha.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 51.6 kDa.
The protein migrates as 66-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (TN2-H5253) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Asp 257 (Accession # P20333-1).
