The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention.
The Biotinylated Human HLA-A*1101 KRASG12D (VVGADGVGK) complex protein is a complex of HLA-A*1101 of the MHC Class I, B2M, and VVGADGVGK peptide of the KRASG12D.
特徴
Alexa Fluor 488-Labeled Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRAS peptide.This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 36.4 kDa and 14.0 kDa.
The protein migrates as 55-60 kDa and <14 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Alexa Fluor 488-Labeled Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein (HLD-HA2H7) is produced via conjugation of AF488 to Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein with a new generation site-specific technology under Star Staining labeling platform. Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVGADGVGK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & VVGADGVGK).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His
Exp Region：Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVGADGVGK peptide
