The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention.
The Biotinylated Human HLA-A*1101 KRASG12D (VVGADGVGK) complex protein is a complex of HLA-A*1101 of the MHC Class I, B2M, and VVGADGVGK peptide of the KRASG12D.
特徴
Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Tetramer Protein is assembled by biotinylated monomer and streptavidin.Biotinylated Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12D peptide.
Biotinylated Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).The protein has a calculated MW of 36.0 kDa and 11.7 kDa.
The protein migrates as 39-43 kDa, 14 kDa and 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Tetramer Protein (HLD-H52H8) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVGADGVGK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & VVGADGVGK).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His
Exp Region：Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVGADGVGK peptide
