The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention.
The Biotinylated Human HLA-A*0301 KRASG12C (VVGACGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVGACGVGK peptide of the KRASG12C.
特徴
Human HLA-A*03:01&B2M&KRASG12C (VVGACGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12C peptide.This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 34.2 kDa and 11.7 kDa.
The protein migrates as 36-41 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Human HLA-A*03:01&B2M&KRASG12C (VVGACGVGK) Complex Protein (HLC-H52H4) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGACGVGK peptide (Accession # P04439 (HLA-A*03:01) & P61769 (B2M) & VVGACGVGK).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His
Exp Region：Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVGACGVGK peptide
