Herpesvirus infections are widely spread throughout the world population.
Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily.
There are two main types of HSV, HSV-1 and HSV-2, which infect humans.
HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections.
Glycoprotein C (gC) is a structural component of the herpes simplex virus type 2 (HSV-2) envelope that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate.
Also plays a role in host immune evasion by inhibiting the host complement cascade activation (By similarity).
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 39.8 kDa.
The protein migrates as 52-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:100ug
Source:HSV-2 (strain 333) Envelope Glycoprotein C (gC), His Tag (GLC-V52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 102 - Glu 446 (Accession # P06475).