It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.
The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 33.2 kDa.
The protein migrates as 47-64 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：SARS coronavirus CUHK-W1 Spike NTD Protein, His Tag (SPD-S52H9) is expressed from human 293 cells (HEK293). It contains AA Asp 17 - Lys 291 (Accession # AAP13567.1).
