Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules.
In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity.
Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 88.3 kDa.
The protein migrates as 95-120 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Biotinylated Cynomolgus Cadherin-17 Protein, His,Avitag (CA7-C82E8) is expressed from human 293 cells (HEK293). It contains AA Lys 30 - Thr 792 (Accession # A0A2K5X8I8-1).
