Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus.
Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle.
Hemagglutinin also plays a major role in the determination of host range restriction and virulence.
As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 64.1 kDa.
The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:1mg
Source:Influenza B [Phuket/3073/2013 (B/Yamagata lineage)] HA Protein, His Tag (HAE-V52H4) is expressed from human 293 cells (HEK293). It contains AA Asp 16- Ser 558 (Accession # EPI529345, GISAID).