GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha.
Low affinity receptor for granulocyte-macrophage colony-stimulating factor.
Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 34.1 kDa.
The protein migrates as 45-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Mouse GM-CSF R alpha Protein, His Tag (GMA-M52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 30 - Pro 327 (Accession # NP_034100.2).
