Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase is a protein that in humans is encoded by the NTRK3 gene.
It belongs to the tropomyosin-related kinase (Trk) family of receptor tyrosine kinases (TrkA, TrkB, and TrkC).TrkC is the high affinity catalytic receptor for the neurotrophin NT-3 (neurotrophin-3).
As such, TrkC mediates the multiple effects of this neurotrophic factor, which includes neuronal differentiation and survival.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 71.2 kDa.
The protein migrates as 95-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human TrkC Protein, Fc Tag (TRC-H5256) is expressed from human 293 cells (HEK293). It contains AA Cys 32 - Thr 429 (Accession # Q16288-1).
