Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules.
In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity.
Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 86.9 kDa.
The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Rat Cadherin-17 Protein, His Tag (CA7-R52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Met 786 (Accession # P55281-1).
