Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules.
In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity.
Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
特徴
This protein carries a mouse IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 111.2 kDa.
The protein migrates as 130-135 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human Cadherin-17 Protein, Mouse IgG1 Fc Tag (CA7-H52A9) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Met 787 (Accession # Q12864-1).
