Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity.
In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2-containing nAChRs.
May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface.
May be involved in the control of anxiety.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 14.1 kDa.
The protein migrates as 18-22 kDa and 35-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human LYPD1 Protein, His,Avitag (LY1-H82E6) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Gly 115 (Accession # Q8N2G4-1).
