Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2).
CXCL2 is 90% identical in amino acid sequence as a related chemokine, CXCL1.
This chemokine is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells.CXCL2 mobilizes cells by interacting with a cell surface chemokine receptor called CXCR2.CXCL2, like related chemokines, is also a powerful neutrophil chemoattractant and is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 34.3 kDa.
The protein migrates as 38-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human CXCL2, Fc Tag (CX2-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 35 - Asn 107 (Accession # P19875).
