FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer.
Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk.
FCGRT possible role in transfer of immunoglobulin G from mother to fetus.
Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 28.3 kDa | 11.5 kDa.
The protein migrates as ＜14.4 kDa and 38-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Canine FCGRT&B2M Heterodimer Protein, His,Avitag&Tag Free (FCM-C82W9) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Pro 298 & Val 28 - Asn 125 (Accession # XP_038512242.1 & NP_001271408.1).
