Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family.
Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney.
Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4.
Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
This protein contains a furin-like convertase cleavage site, 355-RQYR-358, and will be partially processed into N and C-terminal fragment with calculated MW of 38.1 kDa and 49.3 kDa respectively.
The protein migrates as 40 kDa, 60 kDa and 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human Glypican 3, Fc Tag, low endotoxin (GP3-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - His 559 (Accession # P51654-1).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Gln 25 - His 559
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P51654-1
Protein ID：NP_004475.1
Endotoxin：0.1 EU per μg
Purity：90%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
