Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life.
The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera.
The RSV F is a type I viral fusion protein synthesized as inactive, single-chain polypeptides that assemble into trimers.
RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post-fusion conformation.
Both states exhibit epitopes targeted by neutralizing antibodies, and post-fusion RSV F is being developed as a vaccine candidate.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 56.1 kDa.
The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：50ug
Source：FITC-Labeled Human respiratory syncytial virus A (strain A2) Pre-F0, His Tag (RSF-V52H3) is expressed from human 293 cells (HEK293).
Species Reactivity：Human respiratory syncytial virus A (strain A2)
Host：HEK293
Tag：C-10×His
Exp Region：Gln 26- Leu 513
Format：Powder
Conjugate：FITC Labeled
Swiss-Prot：P03420 (N67I, P102A, RELPRFMNYTLNNAKKTNVTLSKKRKRR 109-136 del, S215P, I379V, M447V)
