The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain.
Each polypeptide chain consists of a variable and a constant region.
TRDC is the constant region of T-cell receptor (TCR) delta chain.
It recognizes the non-peptide antigens frequently expressed at the epithelial boundaries, which means the antigens activating γδ T cells are mostly MHC independent.
A wide range of γδ T cell functions have been described in humans and mice, including skin and mucosal epithelial wound repair, induction of tolerance, cytotoxicity and the production of various cytokines that regulate immune responses.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 16.4 kDa.
The protein migrates as 27-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human TRDC, His Tag (TRC-H52H4) is expressed from human 293 cells (HEK293). It contains AA Ser 1 - Val 129 (Accession # B7Z8K6-1).
