83-3880-45 Vibrio cholerae serotype O1 （strain ATCC 39315 / El Tor Inaba N16961） Cholera enterotoxin subunit B Protein, His Tag （MALS verified） 50ug GHB-V52H3-50ug
83-3880-45 Vibrio cholerae serotype O1 （strain ATCC 39315 / El Tor Inaba N16961） Cholera enterotoxin subunit B Protein, His Tag （MALS verified） 50ug GHB-V52H3-50ug
Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae.
It is responsible for the massive, watery diarrhea characteristic of cholera infection.
The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor.
This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells.
The beta chain has no toxic activity by itself.
The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit.
The A subunit contains two chains, A1 and A2, linked by a disulfide bridge.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 13.5 kDa.
The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：50ug
Source：Vibrio cholerae serotype O1 Cholera enterotoxin subunit B, His Tag (GHB-V52H3) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Asn 124 (Accession # P01556).
