B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272.
BTLA contains one Ig-like V-type (immunoglobulin-like) domain.
As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response.
BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 40.2 kDa.
The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human BTLA (31-150) (M105V, G138S, V148M), Fc Tag (BTA-H5254) is expressed from human 293 cells (HEK293). It contains AA Lys 31 - Ser 150 (Accession # AAP44003.1 (M105V, G138S, V148M)).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Lys 31 - Ser 150
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：Q7Z6A9-1
Protein ID：AAP44003.1 (M105V, G138S, V148M)
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
