83-3878-73 Human HTT Protein, MBP,His Tag （MALS verified） 100ug HTT-H51M5-100ug
特徴
- 背景
- Huntingtin is the protein coded for by the HTT gene.
- Autosomal dominant mutation in the Huntingtin (Htt) protein is the cause of Huntington’s Disease (HD).
- In HD, the polyglutamine (polyQ) domain in the N-terminal sequenceof the protein is expanded beyond a threshold of 36 glutamines.
- mutant polyQ expansion strongly correlates in an inverse manner to disease age of onset.
- 特徴
- This protein carries a MBP tag at the N-terminus and a polyhistidine tag at the C-terminus.
- The protein has a calculated MW of 52.7 kDa.
- The protein migrates as 60-63 kDa under reducing (R) condition (SDS-PAGE).
仕様
- 容量：100ug
- Source：Human HTT, MBP,His Tag (HTT-H51M5) is expressed from E. coli cells. It contains AA Met 1 - Glu 82 (Accession # P42858-1).
- Species Reactivity：Human
- Host：E. coli
- Tag：N-MBP & C-10×His
- Exp Region：Met 1 - Glu 82
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：P42858-1
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：20 mM HEPES, 150 mM NaCl, pH7.5
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