83-3878-10 Human Midkine / Mdk Protein, premium grade 500ug MIE-H5117-500ug
特徴
- 背景
- Midkine (MK or MDK), also known as neurite growth-promoting factor 2 (NEGF2), is a protein that in humans is encoded by the MDK gene.
- Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin (NEGF1, 46% homologous with MK).
- It is a nonglycosylated protein, composed of two domains held by disulfide bridges.
- It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine.
- Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair.
- 特徴
- This protein carries no "tag".
- The protein has a calculated MW of 13.6 kDa.
- The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE).
仕様
- 容量：500ug
- Source：Human Midkine Protein, premium grade (MIE-H5117) is expressed from E. coli cells. It contains AA Val 21 - Asp 143 (Accession # P21741-1).
- Species Reactivity：Human
- Host：E. coli
- Tag：Native
- Exp Region：Val 21 - Asp 143
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：P21741
- Endotoxin：0.01 EU per μg
- Purity：90%
- Buffer：PBS, pH7.4
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