CXCL13, originally known as BLC (B-lymphocyte chemoattractant) or BCA-1 (B cell-attracting chemokine 1), is a homeostatic chemokine.
It is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches.
CXCL13 plays a key role in orchestrating cell migration within spatially distinct regions of the secondary lymphoid organs.
It strongly attracts B lymphocytes while promoting migration of only small numbers of T cells and macrophages.
CXCL13 exerts its functions through its receptor CXCR5, which initially, was isolated from Burkitt Lymphoma and therefore designated as Burkitt's lymphoma receptor 1 (BLR1).
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 12.2 kDa.
The protein migrates as 12-15 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
仕様
容量：100ug
Source：Human CXCL13 Protein, His Tag (CX3-H1249) is expressed from E. coli cells. It contains AA Val 23 - Pro 109 (Accession # O43927-1).
