The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 136.2 kDa.
The protein migrates as 160-190 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:50ug
Source:Rhinolophus affinis coronavirus isolate LYRa11 Spike Trimer, His Tag (SPN-R52H3) is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. It contains AA Asp 18 - Pro 1199 (Accession # A0A023PUW9 (R671A, KV972-973PP)).
Species Reactivity:Rhinolophus affinis coronavirus isolate LYRa11