CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily.
CD27 / TNFRSF7 is found in most T-lymphocytes.
CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity.
It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK.
CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 47.7 kDa.
The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human CD27, Fc,Avitag (TN7-H82F6) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Ile 192 (Accession # NP_001233).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc & C-Avi
Exp Region：Thr 21 - Ile 192
Format：Powder
Conjugate：Biotin-labeled
Swiss-Prot：P26842
Protein ID：NP_001233
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
