FOLR4, also know as Sperm-egg fusion protein Juno(IZUMO1R) is receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization.
The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion.
The ligand-receptor interaction probably does not act as a membrane 'fusogen'.
Does not bind folate.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 25.8 kDa.
The protein migrates as 30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human FOLR4, His Tag (FO4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Ser 228 (Accession # A6ND01-1).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His
Exp Region：Gly 20 - Ser 228
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：A6ND01-1
Protein ID：NP_001186135.1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：50 mM Tris, 100 mM Glycine, 500 mM NaCl, pH7.5
