83-3873-16 Human CD27 / TNFRSF7 Protein, Fc Tag （HPLC verified） 200ug CD7-H5254-200ug
特徴
- 背景
- CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily.
- CD27 / TNFRSF7 is found in most T-lymphocytes.
- CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity.
- It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
- This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK.
- CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
- 特徴
- This protein carries a human IgG1 Fc tag at the C-terminus.
- The protein has a calculated MW of 45.9 kDa.
- The protein migrates as 53-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：200ug
- Source：Human CD27, Fc Tag (CD7-H5254) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Ile 192 (Accession # NP_001233).
- Species Reactivity：Human
- Host：HEK293
- Tag：C-Fc
- Exp Region：Thr 21 - Ile 192
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：P26842
- Protein ID：NP_001233
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：50 mM Tris, 100 mM Glycine, pH7.5
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