The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 136.5 kDa.
The protein migrates as 160-190 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：50ug
Source：SARS-CoV GD01 Spike Trimer, His Tag (SPN-S52Ht) is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. It contains AA Ser 14 - Pro 1195 (Accession # AAP51227.1 (R667A, KV968-969PP)).
