The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 137.6 kDa.
The protein migrates as 170-200 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:50ug
Source:Pangolin coronavirus hCoV-19/pangolin/Guangdong/1/2019 Spike Trimer, His Tag (SPN-P52H3) is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. It contains AA Ala 10 - Pro 1205 (Accession # A0A7D6TQ96-1 (R677A, KV978-979AA)).