83-3871-83　［取扱停止］SARS-CoV-2 Spike RBD Protein, His Tag （BA.2/Omicron） （MALS verified） 1mg　SPD-C522n-1mg

特徴

• 背景
• It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.
• The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
• S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
• S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
• 特徴
• This protein carries a polyhistidine tag at the C-terminus.
• The protein has a calculated MW of 26.7 kDa.
• The protein migrates as 33-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

仕様

• 容量：1mg
• Source：SARS-CoV-2 Spike RBD, His Tag (BA.2/Omicron) (SPD-C522n) is expressed from human 293 cells (HEK293). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2; GISAID clade: GRA; Nextstrain clade: 21L).
• Species Reactivity：SARS-CoV-2
• Host：HEK293
• Tag：C-10×His
• Format：Liquid
• Conjugate：Unconjugated
• Protein ID：QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H)
• Endotoxin：1.0 EU per μg
• Purity：95%
• Buffer：PBS, pH7.4
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