The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by a twin strep tag.
The protein has a calculated MW of 141.2 kDa.
The protein migrates as 170-190 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：50ug
Source：Bat coronavirus Spike Trimer, His Tag&Twin-Strep Tag (SPN-B5283) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Gln 1200 (Accession # UAY13253.1 (K978P, V979P)).
