Nucleocapsid (N) protein is the most abundant protein found in coronavirus.
CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways.
It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M.
E., et al.
2017, Virology; 517: 62-68).
The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics.
Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 48.8 kDa.
The protein migrates as 33 kDa and 50-60 kDa under reducing (R) condition (SDS-PAGE).
仕様
容量：25ug
Source：Biotinylated SARS-CoV-2 Nucleocapsid protein, His,Avitag (BA.2*&BA.3*/Omicron) (NUN-C82E9) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1 (P13L, ERS31-33del, R203K, G204R, S413R)). The nucleocapsid mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2; GISAID clade: GRA; Nextstrain clade: 21L & Pango lineage: BA.3; GISAID clade: GRA; Nextstrain clade: 21M).
Species Reactivity：SARS-CoV-2
Host：HEK293
Tag：C-6×His & C-Avi
Exp Region：Met 1 - Ala 419
Format：Powder
Conjugate：Biotin-labeled
Protein ID：QHO62115.1 (P13L, ERS31-33del, R203K, G204R, S413R)
