Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses.
Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2.
B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‑like and Ig C‑like domains with a short cytoplasmic tail.
Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‑type and one C‑type) and shows a ubiquituous expression pattern.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 73.1 kDa.
The protein migrates as 100-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human B7-H3 (4Ig), Fc Tag (B7B-H5258) is expressed from human 293 cells (HEK293). It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1).
