83-3870-45 Mouse 4-1BB Ligand / TNFSF9 Protein, Fc Tag 50ug 41L-M5257-50ug
特徴
- 背景
- Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9.
- 4-1BBL is the high affinity ligand of 4-1BB.
- 4-1BBL induces the proliferation of activated peripheral blood T-cells.
- Also, 4-1BBL may have a role in activation-induced cell death (AICD).
- Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages.
- As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
- 特徴
- This protein carries a human IgG1 Fc tag at the C-terminus.
- The protein has a calculated MW of 49.0 kDa.
- The protein migrates as 64-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：50ug
- Source：Mouse 4-1BB Ligand, Fc Tag (41L-M5257) is expressed from human 293 cells (HEK293). It contains AA Arg 104 - Glu 309 (Accession # NP_033430).
- Species Reactivity：Mouse
- Host：HEK293
- Tag：C-Fc
- Exp Region：Arg 104 - Glu 309
- Format：Powder
- Conjugate：Unconjugated
- Swiss-Prot：P41274
- Protein ID：NP_033430
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
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