Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9.
4-1BBL is the high affinity ligand of 4-1BB.
4-1BBL induces the proliferation of activated peripheral blood T-cells.
Also, 4-1BBL may have a role in activation-induced cell death (AICD).
Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages.
As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
特徴
This protein carries a human IgG1 Fc tag at the N-terminus.
The protein has a calculated MW of 87.4 kDa.
The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Cynomolgus 4-1BB Ligand, Fc Tag (41L-C5254) is expressed from human 293 cells (HEK293). It contains AA Leu 67 - Glu 251 (Accession # XP_015296398.1) trimer design.
Species Reactivity：Cynomolgus
Host：HEK293
Tag：N-Fc
Exp Region：Leu 67 - Glu 251
Format：Powder
Conjugate：Unconjugated
Protein ID：XP_015296398.1
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
