Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility.
It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K+/H+ ATPase pumps into the apical membrane of parietal cells (which in turn increases H+ release into the stomach cavity).
Its release is stimulated by peptides in the lumen of the stomach.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 34.7 kDa.
The protein migrates as 40-45 kDa and 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Mouse Gastrin-71 Protein, Fc tag (GAN-M5253) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Phe 92 (Accession # P48757-1).
