The secretory component (SC) is a unique polypeptide chain that may be found in immunoglobulins A and M (IgA and IgM).
The SC wraps around two IgA units joined by a J chain protein fragment, resulting in a configuration with each of the two antigen binding regions of the two constituent y-shaped antibodies exposed.
One identified function of secretory components is to protect IgA antibodies from degradation by the gastric acids and enzymes of the digestive system.
It also appears that SC may serve in the three-dimensional organization or in the transport and distribution of the resulting IgA complexes.
特徴
This protein carries a twin strep tag at the C-terminus.
The protein has a calculated MW of 67.6 kDa.
The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Human Secretory Component Protein, Strep Tag (SCT-H5280) is expressed from human 293 cells (HEK293). It contains AA Lys 19 - Arg 603 (Accession # P01833-1).
